Cargando…

Apocynin Treatment Prevents Cardiac Connexin 43 Hemichannels Hyperactivity by Reducing Nitroso-Redox Stress in Mdx Mice

Duchenne muscular dystrophy (DMD) is a fatal disease that causes cardiomyopathy and is associated with oxidative stress. In the heart, oxidative stress interferes with the location of connexin 43 (Cx43) to the intercalated discs causing its lateralization to the plasma membrane where Cx43 forms hemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Vielma, Alejandra Z., Boric, Mauricio P., Gonzalez, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432655/
https://www.ncbi.nlm.nih.gov/pubmed/32751416
http://dx.doi.org/10.3390/ijms21155415