Parthenolide Has Negative Effects on In Vitro Enhanced Osteogenic Phenotypes by Inflammatory Cytokine TNF-α via Inhibiting JNK Signaling

Nuclear factor kappa B (NF-κB) regulates inflammatory gene expression and represents a likely target for novel disease treatment approaches, including skeletal disorders. Several plant-derived sesquiterpene lactones can inhibit the activation of NF-κB. Parthenolide (PTL) is an abundant sesquiterpene...

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Detalles Bibliográficos
Autores principales: Park, Jin-Ho, Kang, Young-Hoon, Hwang, Sun-Chul, Oh, Se Heang, Byun, June-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432707/
https://www.ncbi.nlm.nih.gov/pubmed/32751648
http://dx.doi.org/10.3390/ijms21155433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432707/
https://www.ncbi.nlm.nih.gov/pubmed/32751648
http://dx.doi.org/10.3390/ijms21155433

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