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Parthenolide Has Negative Effects on In Vitro Enhanced Osteogenic Phenotypes by Inflammatory Cytokine TNF-α via Inhibiting JNK Signaling
Nuclear factor kappa B (NF-κB) regulates inflammatory gene expression and represents a likely target for novel disease treatment approaches, including skeletal disorders. Several plant-derived sesquiterpene lactones can inhibit the activation of NF-κB. Parthenolide (PTL) is an abundant sesquiterpene...
Autores principales: | Park, Jin-Ho, Kang, Young-Hoon, Hwang, Sun-Chul, Oh, Se Heang, Byun, June-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432707/ https://www.ncbi.nlm.nih.gov/pubmed/32751648 http://dx.doi.org/10.3390/ijms21155433 |
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