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3-Hydroxyolean-12-en-27-oic Acids Inhibit RANKL-Induced Osteoclastogenesis in Vitro and Inflammation-Induced Bone Loss in Vivo

Olean-12-en-27-oic acids possess a variety of pharmacological effects. However, their effects and underlying mechanisms on osteoclastogenesis remain unclear. This study aimed to investigate the anti-osteoclastogenic effects of five olean-12-en-27-oic acid derivatives including 3α,23-isopropylidenedi...

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Detalles Bibliográficos
Autores principales: Seo, Wonyoung, Lee, Suhyun, Tran, Phuong Thao, Ngo, Thi Quynh-Mai, Kim, Okwha, Le, Thanh Huong, Dang, Nguyen Hai, Hwangbo, Cheol, Min, Byung Sun, Lee, Jeong-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432734/
https://www.ncbi.nlm.nih.gov/pubmed/32718089
http://dx.doi.org/10.3390/ijms21155240