α1AMP-Activated Protein Kinase Protects against Lipopolysaccharide-Induced Endothelial Barrier Disruption via Junctional Reinforcement and Activation of the p38 MAPK/HSP27 Pathway

Vascular hyperpermeability is a determinant factor in the pathophysiology of sepsis. While, AMP-activated protein kinase (AMPK) is known to play a role in maintaining endothelial barrier function in this condition. Therefore, we investigated the underlying molecular mechanisms of this protective eff...

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Detalles Bibliográficos
Autores principales: Angé, Marine, Castanares-Zapatero, Diego, De Poortere, Julien, Dufeys, Cécile, Courtoy, Guillaume E., Bouzin, Caroline, Quarck, Rozenn, Bertrand, Luc, Beauloye, Christophe, Horman, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432762/
https://www.ncbi.nlm.nih.gov/pubmed/32759774
http://dx.doi.org/10.3390/ijms21155581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432762/
https://www.ncbi.nlm.nih.gov/pubmed/32759774
http://dx.doi.org/10.3390/ijms21155581

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