Regulation of Filaggrin, Loricrin, and Involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: Pathogenic Implications in Atopic Dermatitis

Atopic dermatitis (AD) is an eczematous, pruritic skin disorder with extensive barrier dysfunction and elevated interleukin (IL)-4 and IL-13 signatures. The barrier dysfunction correlates with the downregulation of barrier-related molecules such as filaggrin (FLG), loricrin (LOR), and involucrin (IV...

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Detalles Bibliográficos
Autor principal: Furue, Masutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432778/
https://www.ncbi.nlm.nih.gov/pubmed/32751111
http://dx.doi.org/10.3390/ijms21155382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432778/
https://www.ncbi.nlm.nih.gov/pubmed/32751111
http://dx.doi.org/10.3390/ijms21155382

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