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VAS3947 Induces UPR-Mediated Apoptosis through Cysteine Thiol Alkylation in AML Cell Lines

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) involvement has been established in the oncogenic cell signaling of acute myeloid leukemia (AML) cells and in the crosstalk with their niche. We have shown an expression of NOX subunits in AML cell lines while NOX activity is lacking...

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Detalles Bibliográficos
Autores principales: El Dor, Maya, Dakik, Hassan, Polomski, Marion, Haudebourg, Eloi, Brachet, Marie, Gouilleux, Fabrice, Prié, Gildas, Zibara, Kazem, Mazurier, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432790/
https://www.ncbi.nlm.nih.gov/pubmed/32751795
http://dx.doi.org/10.3390/ijms21155470