Cargando…
VAS3947 Induces UPR-Mediated Apoptosis through Cysteine Thiol Alkylation in AML Cell Lines
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) involvement has been established in the oncogenic cell signaling of acute myeloid leukemia (AML) cells and in the crosstalk with their niche. We have shown an expression of NOX subunits in AML cell lines while NOX activity is lacking...
Autores principales: | El Dor, Maya, Dakik, Hassan, Polomski, Marion, Haudebourg, Eloi, Brachet, Marie, Gouilleux, Fabrice, Prié, Gildas, Zibara, Kazem, Mazurier, Frédéric |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432790/ https://www.ncbi.nlm.nih.gov/pubmed/32751795 http://dx.doi.org/10.3390/ijms21155470 |
Ejemplares similares
-
Diphenyleneiodonium Triggers Cell Death of Acute Myeloid Leukemia Cells by Blocking the Mitochondrial Respiratory Chain, and Synergizes with Cytarabine
por: Dakik, Hassan, et al.
Publicado: (2022) -
VAS2870 and VAS3947 attenuate platelet activation and thrombus formation via a NOX-independent pathway downstream of PKC
por: Lu, Wan Jung, et al.
Publicado: (2019) -
A Novel Inhibitor of STAT5 Signaling Overcomes Chemotherapy Resistance in Myeloid Leukemia Cells
por: Brachet-Botineau, Marie, et al.
Publicado: (2019) -
Acriflavine targets oncogenic STAT5 signaling in myeloid leukemia cells
por: Hallal, Rawan, et al.
Publicado: (2020) -
Pharmacological Inhibition of Oncogenic STAT3 and STAT5 Signaling in Hematopoietic Cancers
por: Brachet-Botineau, Marie, et al.
Publicado: (2020)