Orally Administered Exosomes Suppress Mouse Delayed-Type Hypersensitivity by Delivering miRNA-150 to Antigen-Primed Macrophage APC Targeted by Exosome-Surface Anti-Peptide Antibody Light Chains

We previously discovered suppressor T cell-derived, antigen (Ag)-specific exosomes inhibiting mouse hapten-induced contact sensitivity effector T cells by targeting antigen-presenting cells (APCs). These suppressive exosomes acted Ag-specifically due to a coating of antibody free light chains (FLC)...

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Detalles Bibliográficos
Autores principales: Nazimek, Katarzyna, Bryniarski, Krzysztof, Ptak, Wlodzimierz, Groot Kormelink, Tom, Askenase, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432818/
https://www.ncbi.nlm.nih.gov/pubmed/32748889
http://dx.doi.org/10.3390/ijms21155540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432818/
https://www.ncbi.nlm.nih.gov/pubmed/32748889
http://dx.doi.org/10.3390/ijms21155540

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