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A Modified Protocol of Diethylnitrosamine Administration in Mice to Model Hepatocellular Carcinoma
We aimed to create an animal model for hepatocellular carcinoma (HCC) with a short time, a high survival rate, as well as a high incidence of HCC in both males and females than previously reported. The Diethylnitrosamine (DEN) model has an age-related effect. A single dose of DEN treatment is not en...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432842/ https://www.ncbi.nlm.nih.gov/pubmed/32751728 http://dx.doi.org/10.3390/ijms21155461 |