The Effect of Novel 7-methyl-5-phenyl-pyrazolo[4,3-e]tetrazolo[4,5-b][1,2,4]triazine Sulfonamide Derivatives on Apoptosis and Autophagy in DLD-1 and HT-29 Colon Cancer Cells

The discovery of cytotoxic drugs is focused on designing a compound structure that directly affects cancer cells without an impact on normal cells. The mechanism of anticancer activity is mainly related with activation of apoptosis. However, recent scientific reports show that autophagy also plays a...

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Detalles Bibliográficos
Autores principales: Gornowicz, Agnieszka, Szymanowska, Anna, Mojzych, Mariusz, Bielawski, Krzysztof, Bielawska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432848/
https://www.ncbi.nlm.nih.gov/pubmed/32717981
http://dx.doi.org/10.3390/ijms21155221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432848/
https://www.ncbi.nlm.nih.gov/pubmed/32717981
http://dx.doi.org/10.3390/ijms21155221

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