UP256 Inhibits Hyperpigmentation by Tyrosinase Expression/Dendrite Formation via Rho-Dependent Signaling and by Primary Cilium Formation in Melanocytes

Skin hyperpigmentation is generally characterized by increased synthesis and deposition of melanin in the skin. UP256, containing bakuchiol, is a well-known medication for acne vulgaris. Acne sometimes leaves dark spots on the skin, and we hypothesized that UP256 may be effective against hyperpigmen...

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Detalles Bibliográficos
Autores principales: Kang, Min Cheol, Lee, Jae-Wook, Lee, Taek Hwan, Subedi, Lalita, Wahedi, Hussain M., Do, Seon-Gil, Shin, Eunju, Moon, Eun-Yi, Kim, Sun Yeou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432859/
https://www.ncbi.nlm.nih.gov/pubmed/32731326
http://dx.doi.org/10.3390/ijms21155341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432859/
https://www.ncbi.nlm.nih.gov/pubmed/32731326
http://dx.doi.org/10.3390/ijms21155341

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