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UP256 Inhibits Hyperpigmentation by Tyrosinase Expression/Dendrite Formation via Rho-Dependent Signaling and by Primary Cilium Formation in Melanocytes

Skin hyperpigmentation is generally characterized by increased synthesis and deposition of melanin in the skin. UP256, containing bakuchiol, is a well-known medication for acne vulgaris. Acne sometimes leaves dark spots on the skin, and we hypothesized that UP256 may be effective against hyperpigmen...

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Detalles Bibliográficos
Autores principales:	Kang, Min Cheol, Lee, Jae-Wook, Lee, Taek Hwan, Subedi, Lalita, Wahedi, Hussain M., Do, Seon-Gil, Shin, Eunju, Moon, Eun-Yi, Kim, Sun Yeou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432859/ https://www.ncbi.nlm.nih.gov/pubmed/32731326 http://dx.doi.org/10.3390/ijms21155341

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