Investigation of Strand-Selective Interaction of SNA-Modified siRNA with AGO2-MID

Small interfering RNA (siRNA) has been recognized as a powerful gene-silencing tool. For therapeutic application, chemical modification is often required to improve the properties of siRNA, including its nuclease resistance, activity, off-target effects, and tissue distribution. Careful siRNA guide...

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Detalles Bibliográficos
Autores principales: Kamiya, Yukiko, Takeyama, Yuuki, Mizuno, Tomonari, Satoh, Fuminori, Asanuma, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432901/
https://www.ncbi.nlm.nih.gov/pubmed/32717920
http://dx.doi.org/10.3390/ijms21155218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432901/
https://www.ncbi.nlm.nih.gov/pubmed/32717920
http://dx.doi.org/10.3390/ijms21155218

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