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A Tissue-Engineered Human Psoriatic Skin Model to Investigate the Implication of cAMP in Psoriasis: Differential Impacts of Cholera Toxin and Isoproterenol on cAMP Levels of the Epidermis

Pathological and healthy skin models were reconstructed using similar culture conditions according to well-known tissue engineering protocols. For both models, cyclic nucleotide enhancers were used as additives to promote keratinocytes’ proliferation. Cholera toxin (CT) and isoproterenol (ISO), a be...

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Detalles Bibliográficos
Autores principales: Simard, Mélissa, Morin, Sophie, Rioux, Geneviève, Séguin, Rachelle, Loing, Estelle, Pouliot, Roxane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432929/
https://www.ncbi.nlm.nih.gov/pubmed/32717879
http://dx.doi.org/10.3390/ijms21155215