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Exploration of multi‐target effects of 3‐benzoyl‐5‐hydroxychromen‐2‐one in Alzheimer’s disease cell and mouse models

Microtubule‐associated protein Tau, abundant in the central nervous system (CNS), plays crucial roles in microtubule assembly and stabilization. Abnormal Tau phosphorylation and aggregation are a common pathogenic hallmark in Alzheimer's disease (AD). Hyperphosphorylation of Tau could change it...

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Detalles Bibliográficos
Autores principales: Lin, Te‐Hsien, Chiu, Ya‐Jen, Lin, Chih‐Hsin, Lin, Chung‐Yin, Chao, Chih‐Ying, Chen, Yu‐Chieh, Yang, Shu‐Mei, Lin, Wenwei, Mei Hsieh‐Li, Hsiu, Wu, Yih‐Ru, Chang, Kuo‐Hsuan, Lee‐Chen, Guey‐Jen, Chen, Chiung‐Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433010/
https://www.ncbi.nlm.nih.gov/pubmed/32496635
http://dx.doi.org/10.1111/acel.13169