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Dynamic nanopore long-read sequencing analysis of HIV-1 splicing events during the early steps of infection
BACKGROUND: Alternative splicing is a key step in Human Immunodeficiency Virus type 1 (HIV-1) replication that is tightly regulated both temporally and spatially. More than 50 different transcripts can be generated from a single HIV-1 unspliced pre-messenger RNA (pre-mRNA) and a balanced proportion...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433067/ https://www.ncbi.nlm.nih.gov/pubmed/32807178 http://dx.doi.org/10.1186/s12977-020-00533-1 |