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Dynamic nanopore long-read sequencing analysis of HIV-1 splicing events during the early steps of infection

BACKGROUND: Alternative splicing is a key step in Human Immunodeficiency Virus type 1 (HIV-1) replication that is tightly regulated both temporally and spatially. More than 50 different transcripts can be generated from a single HIV-1 unspliced pre-messenger RNA (pre-mRNA) and a balanced proportion...

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Detalles Bibliográficos
Autores principales: Nguyen Quang, Nam, Goudey, Sophie, Ségéral, Emmanuel, Mohammad, Ammara, Lemoine, Sophie, Blugeon, Corinne, Versapuech, Margaux, Paillart, Jean-Christophe, Berlioz-Torrent, Clarisse, Emiliani, Stéphane, Gallois-Montbrun, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433067/
https://www.ncbi.nlm.nih.gov/pubmed/32807178
http://dx.doi.org/10.1186/s12977-020-00533-1