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Exosomes derived from mesenchymal stem cells improved core symptoms of genetically modified mouse model of autism Shank3B

BACKGROUND: Partial or an entire deletion of SHANK3 are considered as major drivers in the Phelan–McDermid syndrome, in which 75% of patients are diagnosed with autism spectrum disorder (ASD). During the recent years, there was an increasing interest in stem cell therapy in ASD, and specifically, me...

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Detalles Bibliográficos
Autores principales: Perets, N., Oron, O., Herman, S., Elliott, E., Offen, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433169/
https://www.ncbi.nlm.nih.gov/pubmed/32807217
http://dx.doi.org/10.1186/s13229-020-00366-x