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Undercarboxylated osteocalcin correlates with insulin secretion in Japanese individuals with diabetes

BACKGROUND: Undercarboxylated osteocalcin (ucOC) is a secreted protein produced by osteoblasts that regulates insulin secretion and insulin sensitivity in rodents. However, the significance of these effects on glucose metabolism in human remains unknown. Moreover, the pathophysiological roles of ucO...

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Detalles Bibliográficos
Autores principales: Funakoshi, Shogo, Yoshimura, Kumiko, Hirano, Seiki, Ohmi, Satoko, Amano, Eri, Fukuda, Yoshiharu, Terada, Yoshio, Fujimoto, Shimpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433182/
https://www.ncbi.nlm.nih.gov/pubmed/32821293
http://dx.doi.org/10.1186/s13098-020-00579-3