Cargando…

Methods for copy number aberration detection from single-cell DNA-sequencing data

Copy number aberrations (CNAs), which are pathogenic copy number variations (CNVs), play an important role in the initiation and progression of cancer. Single-cell DNA-sequencing (scDNAseq) technologies produce data that is ideal for inferring CNAs. In this review, we review eight methods that have...

Descripción completa

Detalles Bibliográficos
Autores principales: Mallory, Xian F., Edrisi, Mohammadamin, Navin, Nicholas, Nakhleh, Luay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433197/
https://www.ncbi.nlm.nih.gov/pubmed/32807205
http://dx.doi.org/10.1186/s13059-020-02119-8