An integrative pan-cancer investigation reveals common genetic and transcriptional alterations of AMPK pathway genes as important predictors of clinical outcomes across major cancer types

BACKGROUND: The AMP-activated protein kinase (AMPK) is an evolutionarily conserved regulator of cellular energy homeostasis. As a nexus for transducing metabolic signals, AMPK cooperates with other energy-sensing pathways to modulate cellular responses to metabolic stressors. With metabolic reprogra...

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Detalles Bibliográficos
Autores principales: Chang, Wai Hoong, Lai, Alvina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433212/
https://www.ncbi.nlm.nih.gov/pubmed/32807122
http://dx.doi.org/10.1186/s12885-020-07286-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433212/
https://www.ncbi.nlm.nih.gov/pubmed/32807122
http://dx.doi.org/10.1186/s12885-020-07286-2

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