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Case report: Emergence of dolutegravir resistance in a patient on second-line antiretroviral therapy

INTRODUCTION: The integrase strand transfer inhibitor dolutegravir (DTG) has a high genetic barrier to resistance. Only rare cases of resistance to DTG have been reported when it is used as a component of antiretroviral therapy regimens in treatment-experienced patients unless there was prior use of...

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Detalles Bibliográficos
Autores principales: Mahomed, Kairoonisha, Wallis, Carole L., Dunn, Liezl, Maharaj, Shavani, Maartens, Gary, Meintjes, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433307/
https://www.ncbi.nlm.nih.gov/pubmed/32832110
http://dx.doi.org/10.4102/sajhivmed.v21i1.1062