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Anxiety and Startle Phenotypes in Glrb Spastic and Glra1 Spasmodic Mouse Mutants

A GWAS study recently demonstrated single nucleotide polymorphisms (SNPs) in the human GLRB gene of individuals with a prevalence for agoraphobia. GLRB encodes the glycine receptor (GlyRs) β subunit. The identified SNPs are localized within the gene flanking regions (3′ and 5′ UTRs) and intronic reg...

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Detalles Bibliográficos
Autores principales: Schaefer, Natascha, Signoret-Genest, Jérémy, von Collenberg, Cora R., Wachter, Britta, Deckert, Jürgen, Tovote, Philip, Blum, Robert, Villmann, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433344/
https://www.ncbi.nlm.nih.gov/pubmed/32848605
http://dx.doi.org/10.3389/fnmol.2020.00152