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Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer

BACKGROUND: Emerging evidence suggests the involvement of Reelin in chemoresistance in various cancers. However, its function in cisplatin (DDP) sensitivity of non-small cell lung cancer (NSCLC) needs to be investigated. MATERIAL/METHODS: Reelin expression in cisplatin-sensitive A549 cells and cispl...

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Detalles Bibliográficos
Autores principales: Li, Ji-Min, Yang, Fang, Li, Juan, Yuan, Wei-Qi, Wang, Hao, Luo, Yi-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433388/
https://www.ncbi.nlm.nih.gov/pubmed/32764530
http://dx.doi.org/10.12659/MSM.925298