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Silencing of Long Non-coding RNA NEAT1 Upregulates miR-195a to Attenuate Intervertebral Disk Degeneration via the BAX/BAK Pathway

BACKGROUND/AIMS: An increasing body of evidence has demonstrated that long non-coding RNAs (lncRNAs) play a vital regulatory role in intervertebral disk degeneration (IVDD). Nucleus enriched abundant transcript 1 (NEAT1), a novel cancer-related lncRNA, is associated with many malignancies, including...

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Detalles Bibliográficos
Autores principales: Tang, Ning, Dong, Yulei, Liu, Jiaming, Zhao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433405/
https://www.ncbi.nlm.nih.gov/pubmed/32850952
http://dx.doi.org/10.3389/fmolb.2020.00147