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Evaluation of a TrkB agonist on spatial and motor learning in the Ube3a mouse model of Angelman syndrome
Angelman syndrome is a rare neurodevelopmental disorder caused by a mutation in the maternal allele of the gene Ube3a. The primary symptoms of Angelman syndrome are severe cognitive deficits, impaired motor functions, and speech disabilities. Analogous phenotypes have been detected in young adult Ub...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433657/ https://www.ncbi.nlm.nih.gov/pubmed/32817301 http://dx.doi.org/10.1101/lm.051201.119 |