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Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice

Individual differences in cognitive decline during normal aging and Alzheimer's disease (AD) are common, but the molecular mechanisms underlying these distinct outcomes are not fully understood. We utilized a combination of genetic, molecular, and behavioral data from a mouse population designe...

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Detalles Bibliográficos
Autores principales: Heuer, Sarah E., Neuner, Sarah M., Hadad, Niran, O'Connell, Kristen M.S., Williams, Robert W., Philip, Vivek M., Gaiteri, Chris, Kaczorowski, Catherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433658/
https://www.ncbi.nlm.nih.gov/pubmed/32817302
http://dx.doi.org/10.1101/lm.051839.120