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High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires

The collection of T cell receptors (TCRs) generated by somatic recombination is large but unknown. We generate large TCR repertoire datasets as a resource to facilitate detailed studies of the role of TCR clonotypes and repertoires in health and disease. We estimate the size of individual human reco...

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Detalles Bibliográficos
Autores principales: Soto, Cinque, Bombardi, Robin G., Kozhevnikov, Morgan, Sinkovits, Robert S., Chen, Elaine C., Branchizio, Andre, Kose, Nurgun, Day, Samuel B., Pilkinton, Mark, Gujral, Madhusudan, Mallal, Simon, Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433715/
https://www.ncbi.nlm.nih.gov/pubmed/32668251
http://dx.doi.org/10.1016/j.celrep.2020.107882