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High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires
The collection of T cell receptors (TCRs) generated by somatic recombination is large but unknown. We generate large TCR repertoire datasets as a resource to facilitate detailed studies of the role of TCR clonotypes and repertoires in health and disease. We estimate the size of individual human reco...
Autores principales: | Soto, Cinque, Bombardi, Robin G., Kozhevnikov, Morgan, Sinkovits, Robert S., Chen, Elaine C., Branchizio, Andre, Kose, Nurgun, Day, Samuel B., Pilkinton, Mark, Gujral, Madhusudan, Mallal, Simon, Crowe, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433715/ https://www.ncbi.nlm.nih.gov/pubmed/32668251 http://dx.doi.org/10.1016/j.celrep.2020.107882 |
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