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Optimization and validation of a modified radial-arm water maze protocol using a murine model of mild closed head traumatic brain injury

Cognitive impairments can be a significant problem after a traumatic brain injury (TBI), which affects millions worldwide each year. There is a need for establish reproducible cognitive assays in rodents to better understand disease mechanisms and to develop therapeutic interventions towards treatin...

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Detalles Bibliográficos
Autores principales: Macheda, Teresa, Roberts, Kelly N., Morganti, Josh M., Braun, David J., Bachstetter, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433858/
https://www.ncbi.nlm.nih.gov/pubmed/32810143
http://dx.doi.org/10.1371/journal.pone.0232862