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A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice

Arthritogenic alphaviruses cause debilitating musculoskeletal disease and historically have circulated in distinct regions. With the global spread of chikungunya virus (CHIKV), there now is more geographic overlap, which could result in heterologous immunity affecting natural infection or vaccinatio...

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Detalles Bibliográficos
Autores principales: Fox, Julie M., Huang, Ling, Tahan, Stephen, Powell, Laura A., Crowe, James E., Wang, David, Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7433899/
https://www.ncbi.nlm.nih.gov/pubmed/32760128
http://dx.doi.org/10.1371/journal.ppat.1008743