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Alternative splicing of coq-2 controls the levels of rhodoquinone in animals

Parasitic helminths use two benzoquinones as electron carriers in the electron transport chain. In normoxia, they use ubiquinone (UQ), but in anaerobic conditions inside the host, they require rhodoquinone (RQ) and greatly increase RQ levels. We previously showed the switch from UQ to RQ synthesis i...

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Detalles Bibliográficos
Autores principales: Tan, June H, Lautens, Margot, Romanelli-Cedrez, Laura, Wang, Jianbin, Schertzberg, Michael R, Reinl, Samantha R, Davis, Richard E, Shepherd, Jennifer N, Fraser, Andrew G, Salinas, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434440/
https://www.ncbi.nlm.nih.gov/pubmed/32744503
http://dx.doi.org/10.7554/eLife.56376