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Alternative splicing of coq-2 controls the levels of rhodoquinone in animals
Parasitic helminths use two benzoquinones as electron carriers in the electron transport chain. In normoxia, they use ubiquinone (UQ), but in anaerobic conditions inside the host, they require rhodoquinone (RQ) and greatly increase RQ levels. We previously showed the switch from UQ to RQ synthesis i...
Autores principales: | Tan, June H, Lautens, Margot, Romanelli-Cedrez, Laura, Wang, Jianbin, Schertzberg, Michael R, Reinl, Samantha R, Davis, Richard E, Shepherd, Jennifer N, Fraser, Andrew G, Salinas, Gustavo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434440/ https://www.ncbi.nlm.nih.gov/pubmed/32744503 http://dx.doi.org/10.7554/eLife.56376 |
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