TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex

BCL9 and PYGO are β-catenin cofactors that enhance the transcription of Wnt target genes. They have been proposed as therapeutic targets to diminish Wnt signaling output in intestinal malignancies. Here we find that, in colorectal cancer cells and in developing mouse forelimbs, BCL9 proteins sustain...

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Detalles Bibliográficos
Autores principales: Zimmerli, Dario, Borrelli, Costanza, Jauregi-Miguel, Amaia, Söderholm, Simon, Brütsch, Salome, Doumpas, Nikolaos, Reichmuth, Jan, Murphy-Seiler, Fabienne, Aguet, MIchel, Basler, Konrad, Moor, Andreas E, Cantù, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434441/
https://www.ncbi.nlm.nih.gov/pubmed/32808927
http://dx.doi.org/10.7554/eLife.58123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434441/
https://www.ncbi.nlm.nih.gov/pubmed/32808927
http://dx.doi.org/10.7554/eLife.58123

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