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Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress

Pathogens find diverse niches for survival including inside a host cell where replication occurs in a relatively protective environment. Vibrio parahaemolyticus is a facultative intracellular pathogen that uses its type 3 secretion system 2 (T3SS2) to invade and replicate inside host cells. Analysis...

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Detalles Bibliográficos
Autores principales: Chimalapati, Suneeta, de Souza Santos, Marcela, Lafrance, Alexander E, Ray, Ann, Lee, Wan-Ru, Rivera-Cancel, Giomar, Vale, Gonçalo, Pawlowski, Krzysztof, Mitsche, Matthew A, McDonald, Jeffrey G, Liou, Jen, Orth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434443/
https://www.ncbi.nlm.nih.gov/pubmed/32808593
http://dx.doi.org/10.7554/eLife.58057