Tocilizumab improves oxidative stress and endothelial glycocalyx: A mechanism that may explain the effects of biological treatment on COVID-19

We investigated the effects of tocilizumab on endothelial glycocalyx, a determinant of vascular permeability, and myocardial function in rheumatoid arthritis (RA). Eighty RA patients were randomized to tocilizumab (n = 40) or conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) an...

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Detalles Bibliográficos
Autores principales: Ikonomidis, Ignatios, Pavlidis, George, Katsimbri, Pelagia, Lambadiari, Vaia, Parissis, John, Andreadou, Ioanna, Tsoumani, Maria, Boumpas, Dimitrios, Kouretas, Dimitrios, Iliodromitis, Efstathios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434461/
https://www.ncbi.nlm.nih.gov/pubmed/32822775
http://dx.doi.org/10.1016/j.fct.2020.111694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434461/
https://www.ncbi.nlm.nih.gov/pubmed/32822775
http://dx.doi.org/10.1016/j.fct.2020.111694

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