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Human Adipose Tissue-Derived Mesenchymal Stem Cells in Parkinson’s Disease: Inhibition of T Helper 17 Cell Differentiation and Regulation of Immune Balance Towards a Regulatory T Cell Phenotype

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disorder displaying a typical neuroinflammation pathology that may result from an imbalance between regulatory T cells (Treg) and T helper 17 (Th17) cells. Human adipose tissue-derived mesenchymal stem cells (Ad-MSCs) exert immunomodulatory...

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Detalles Bibliográficos
Autores principales: Bi, Yong, Lin, Xiaobin, Liang, Huazheng, Yang, Dehao, Zhang, Xiaowei, Ke, Jianming, Xiao, Jingjing, Chen, Zhilin, Chen, Weian, Zhang, Xu, Wang, Shaoshi, Liu, Chun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434526/
https://www.ncbi.nlm.nih.gov/pubmed/32884248
http://dx.doi.org/10.2147/CIA.S259762