POLE and POLD1 germline exonuclease domain pathogenic variants, a rare event in colorectal cancer from the Middle East

BACKGROUND: Colorectal cancer (CRC) is a major contributor to morbidity and mortality related to cancer. Only ~5% of all CRCs occur as a result of pathogenic variants in well‐defined CRC predisposing genes. The frequency and effect of exonuclease domain pathogenic variants of POLE and POLD1 genes in...

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Detalles Bibliográficos
Autores principales: Siraj, Abdul K., Bu, Rong, Iqbal, Kaleem, Parvathareddy, Sandeep K., Masoodi, Tariq, Siraj, Nabil, Al‐Rasheed, Maha, Kong, Yan, Ahmed, Saeeda O., Al‐Obaisi, Khadija A. S., Victoria, Ingrid G., Arshad, Maham, Al‐Dayel, Fouad, Abduljabbar, Alaa, Ashari, Luai H., Al‐Kuraya, Khawla S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434734/
https://www.ncbi.nlm.nih.gov/pubmed/32567205
http://dx.doi.org/10.1002/mgg3.1368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434734/
https://www.ncbi.nlm.nih.gov/pubmed/32567205
http://dx.doi.org/10.1002/mgg3.1368

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