A TOMM40/APOE allele encoding APOE‐E3 predicts high likelihood of late‐onset Alzheimer’s disease in autopsy cases

BACKGROUND: The APOE‐ε4 allele is an established risk factor for Alzheimer's disease (AD). TOMM40 located adjacent to APOE has also been implicated in AD but reports of TOMM40 associations with AD that are independent of APOE‐ε4 are at variance. METHODS: We investigated associations of AD with...

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Detalles Bibliográficos
Autores principales: Soyal, Selma M., Kwik, Markus, Kalev, Ognian, Lenz, Stefan, Zara, Greta, Strasser, Peter, Patsch, Wolfgang, Weis, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434743/
https://www.ncbi.nlm.nih.gov/pubmed/32472747
http://dx.doi.org/10.1002/mgg3.1317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434743/
https://www.ncbi.nlm.nih.gov/pubmed/32472747
http://dx.doi.org/10.1002/mgg3.1317

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