Promoter Hypomethylation and miR-145-5p Downregulation- Mediated HDAC11 Overexpression Promotes Sorafenib Resistance and Metastasis of Hepatocellular Carcinoma Cells

Sorafenib resistance and tumor metastasis account for poor outcome of hepatocellular carcinoma (HCC). Histone deacetylase 11 (HDAC11) has been reported to exert oncogenic effects in several types of human cancer, but its specific functions and detailed mechanisms in HCC are not fully elucidated. Her...

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Detalles Bibliográficos
Autores principales: Wang, Wenlong, Ding, Bisha, Lou, Weiyang, Lin, Shengyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434871/
https://www.ncbi.nlm.nih.gov/pubmed/32903337
http://dx.doi.org/10.3389/fcell.2020.00724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434871/
https://www.ncbi.nlm.nih.gov/pubmed/32903337
http://dx.doi.org/10.3389/fcell.2020.00724

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