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Interaction of the pioneer transcription factor GATA3 with nucleosomes

During cellular reprogramming, the pioneer transcription factor GATA3 binds chromatin, and in a context-dependent manner directs local chromatin remodeling and enhancer formation. Here, we use high-resolution nucleosome mapping in human cells to explore the impact of the position of GATA motifs on t...

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Detalles Bibliográficos
Autores principales: Tanaka, Hiroki, Takizawa, Yoshimasa, Takaku, Motoki, Kato, Daiki, Kumagawa, Yusuke, Grimm, Sara A., Wade, Paul A., Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434886/
https://www.ncbi.nlm.nih.gov/pubmed/32811816
http://dx.doi.org/10.1038/s41467-020-17959-y