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Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy
The systemic decline in autophagic activity with age impairs homeostasis in several tissues, leading to age-related diseases. A mechanistic understanding of adipocyte dysfunction with age could help to prevent age-related metabolic disorders, but the role of autophagy in aged adipocytes remains uncl...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434891/ https://www.ncbi.nlm.nih.gov/pubmed/32811819 http://dx.doi.org/10.1038/s41467-020-17985-w |