Innovative prolonged-release oral alkalising formulation allowing sustained urine pH increase with twice daily administration: randomised trial in healthy adults

A multi-particulate fixed-dose combination product, consisting of a combination of two alkalising salts formulated as prolonged-release granules, ADV7103, was developed to obtain a sustained and prolonged alkalising effect. The specific release of both types of granules was shown in vitro through th...

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Detalles Bibliográficos
Autores principales: Guittet, C., Roussel-Maupetit, C., Manso-Silván, M. A., Guillaumin, F., Vandenhende, F., Granier, L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434908/
https://www.ncbi.nlm.nih.gov/pubmed/32811843
http://dx.doi.org/10.1038/s41598-020-70549-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434908/
https://www.ncbi.nlm.nih.gov/pubmed/32811843
http://dx.doi.org/10.1038/s41598-020-70549-2

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