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Inhibition of HDAC increases BDNF expression and promotes neuronal rewiring and functional recovery after brain injury

Brain injury causes serious motor, sensory, and cognitive disabilities. Accumulating evidence has demonstrated that histone deacetylase (HDAC) inhibitors exert neuroprotective effects against various insults to the central nervous system (CNS). In this study, we investigated the effects of the HDAC...

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Detalles Bibliográficos
Autores principales: Sada, Naoki, Fujita, Yuki, Mizuta, Nanano, Ueno, Masaki, Furukawa, Takahisa, Yamashita, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434917/
https://www.ncbi.nlm.nih.gov/pubmed/32811822
http://dx.doi.org/10.1038/s41419-020-02897-w