Key role of quinone in the mechanism of respiratory complex I

Complex I is the first and the largest enzyme of respiratory chains in bacteria and mitochondria. The mechanism which couples spatially separated transfer of electrons to proton translocation in complex I is not known. Here we report five crystal structures of T. thermophilus enzyme in complex with...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Fernández, Javier, Kaszuba, Karol, Minhas, Gurdeep S., Baradaran, Rozbeh, Tambalo, Margherita, Gallagher, David T., Sazanov, Leonid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434922/
https://www.ncbi.nlm.nih.gov/pubmed/32811817
http://dx.doi.org/10.1038/s41467-020-17957-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434922/
https://www.ncbi.nlm.nih.gov/pubmed/32811817
http://dx.doi.org/10.1038/s41467-020-17957-0

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