Designing Safer CRISPR/Cas9 Therapeutics for HIV: Defining Factors That Regulate and Technologies Used to Detect Off-Target Editing

Human immunodeficiency virus type-1 (HIV-1) infection has resulted in the death of upward of 39 million people since being discovered in the early 1980s. A cure strategy for HIV-1 has eluded scientists, but gene editing technologies such as clustered regularly interspaced short palindromic repeats (...

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Detalles Bibliográficos
Autores principales: Sullivan, Neil T., Allen, Alexander G., Atkins, Andrew J., Chung, Cheng-Han, Dampier, Will, Nonnemacher, Michael R., Wigdahl, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434968/
https://www.ncbi.nlm.nih.gov/pubmed/32903440
http://dx.doi.org/10.3389/fmicb.2020.01872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434968/
https://www.ncbi.nlm.nih.gov/pubmed/32903440
http://dx.doi.org/10.3389/fmicb.2020.01872

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