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Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity

Species longevity varies significantly across animal species, but the underlying molecular mechanisms remain poorly understood. Recent studies and omics approaches suggest that phenotypic traits of longevity could converge in the mammalian target of rapamycin (mTOR) signalling pathway. The present s...

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Detalles Bibliográficos
Autores principales: Mota-Martorell, Natalia, Jove, Mariona, Pradas, Irene, Berdún, Rebeca, Sanchez, Isabel, Naudi, Alba, Gari, Eloi, Barja, Gustavo, Pamplona, Reinald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434991/
https://www.ncbi.nlm.nih.gov/pubmed/32578071
http://dx.doi.org/10.1007/s11357-020-00210-3