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Divergent effects of glutathione depletion on isocitrate dehydrogenase 1 and the pentose phosphate pathway in hamster liver

The liver regenerates NADPH via multiple pathways to maintain redox balance and reductive biosynthesis. The pentose phosphate pathway (PPP) contributes to hepatic lipogenesis by supplying NADPH, and it is thought to play a major role in response to oxidative stress. This study determined the signifi...

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Detalles Bibliográficos
Autores principales: Jin, Eunsook S., Lee, Min H., Malloy, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435027/
https://www.ncbi.nlm.nih.gov/pubmed/32812387
http://dx.doi.org/10.14814/phy2.14554