Cytoskeletal remodeling slows cross‐bridge cycling and ATP hydrolysis rates in airway smooth muscle

During isometric activation of airway smooth muscle (ASM), cross‐bridge cycling and ATP hydrolysis rates decline across time even though isometric force is sustained. Thus, tension cost (i.e., ATP hydrolysis rate per unit of force during activation) decreases with time. The “latch‐state” hypothesis...

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Detalles Bibliográficos
Autores principales: Delmotte, Philippe, Han, Young‐soo, Sieck, Gary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435030/
https://www.ncbi.nlm.nih.gov/pubmed/32812390
http://dx.doi.org/10.14814/phy2.14561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435030/
https://www.ncbi.nlm.nih.gov/pubmed/32812390
http://dx.doi.org/10.14814/phy2.14561

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