Recombinant KRAS G12D Protein Vaccines Elicit Significant Anti-Tumor Effects in Mouse CT26 Tumor Models

Drug development targeting the most frequently mutation G12D of KRAS has great significance. As an attractive immunotherapy, cancer vaccines can overcome binding difficulties of small molecules; however, the weak immunogenicity and production difficulties of reported KRAS mutation vaccines limit the...

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Detalles Bibliográficos
Autores principales: Wan, Yuhua, Zhang, Yan, Wang, Gengchong, Mwangi, Patrick Malonza, Cai, Huaman, Li, Rongxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435050/
https://www.ncbi.nlm.nih.gov/pubmed/32903495
http://dx.doi.org/10.3389/fonc.2020.01326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435050/
https://www.ncbi.nlm.nih.gov/pubmed/32903495
http://dx.doi.org/10.3389/fonc.2020.01326

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